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GENERIC PROZAC: fluoxetine (flew OX e teen)
Brand Names: Prozac, Prozac Weekly, Sarafem


Fluoxetine - generic Prozac - is an antidepressant medication originally approved by the FDA in 1987 and currently available for the treatment of depression, obsessive-compulsive disorder, and bulimia nervosa. This medication for depression has also been used to treat panic disorder. Fluoxetine medication for depression is believed to work by blocking the reabsorption of serotonin, a neurotransmitter or chemical messenger in the brain. It is a member of the serotonin-reuptake inhibitor (SSRI) family, as are Zoloft (sertraline) and Paxil (paroxetine).

DOSING: Fluoxetine is used in the treatment of depression and obsessive-compulsive disorders. It usually is taken once or twice daily; however, it also has been taken once weekly. Fluoxetine should be taken with food at doses specifically directed by your physician. Individual doses vary greatly between individuals. If discontinued you should gradually withdraw from this medication as directed by your doctor.

SIDE EFFECTS: Fluoxetine as with most antidepressants can cause nausea, headaches, anxiety, insomnia, drowsiness, and loss of appetite. Fluoxetine has been implicated in serious skin rashes and vasculitis. Increased blood pressure can occur and should be monitored. Seizures have been reported. Life-threatening interactions can occur in combination with MAO inhibitors, such as nardil and parnate. MAO inhibitors and fluoxetine should not be taken together and a waiting period of 14 days between taking these two classes of medications is strongly advised.

"If antidepressants are discontinued abruptly, symptoms may occur such as dizziness, headache, nausea, changes in mood, or changes in the sense of smell, taste, etc. (Such symptoms even may occur when even a few doses of antidepressant are missed.) Therefore, it is recommended that the dose of antidepressant be reduced gradually when therapy is discontinued.".

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